Despite many challenges, Bangladesh has made considerable progress over the last two decades in improving the health status of the citizen. Population health outcomes have shown marked improvement, with falls in maternal, infant and under-five mortality rates. There are significant reductions in total fertility rate, high levels of immunization have been achieved and life expectancy is increasing. These improvements in health sector can be attributed to a number of health and non-health related factors such as delivery in a health facility, childhood immunization, management of diarrhoea with oral rehydration salts, women’s education, health care-seeking behaviour and improved economic circumstances. However, the persisting inequality, prolonged waiting time and weak referral mechanism is a concern. Poor population from rural, remote and hard to reach areas rarely use high quality health care services and experience higher rates of mortality and morbidity. Though Bangladesh has made dramatic improvement in health sector, further improvement in health will certainly require innovations. Innovation in health is needed for strengthening the health systems and/or to improve the health outcome. To address health sector issues, a2i in collaboration with DGHS is announcing a request for applications for its small grants program to improve the quality of care and health state of the population. A2i will issue grants of up to 25,00,000 BDT to support the costs of piloting awarded research project.